Gastric Tissue Biopsy and Culture


Gastric Tissue Biopsy and Culture

What is a gastric tissue biopsy and culture?

A gastric tissue biopsy and culture are laboratory tests that examine stomach tissue. These tests are typically carried out to determine the cause of a stomach ulcer or other troublesome stomach symptoms.

“Gastric tissue biopsy” is the term used for the examination of tissue removed from your stomach. For a gastric tissue culture, the tissue is placed in a special dish to see if bacteria or other organisms grow.

Read more: Stomach ulcer »

Tissue samples from your stomach are obtained during an endoscopic exam. In this procedure, a long, flexible tube with a small camera (endoscope) is inserted down your throat and esophagus and into your stomach and upper small intestine (duodenum).

With the endoscope, your doctor can view your stomach for irregularities and remove tissue samples for biopsy and culture. The samples are then analyzed for the presence of infections or cancerous cells and signs of inflammation.

Purpose of gastric tissue biopsy and culture

Your doctor may order a gastric tissue biopsy and culture if you’re experiencing any of these symptoms:

  • pain in your upper stomach
  • nausea or vomiting
  • loss of appetite
  • unexplained weight loss
  • black stools

These laboratory tests can help diagnose cancer and infections, including Helicobacter pylori (H. pylori) infection, which can cause ulcers of the stomach.

peptic ulcers. About half the world’s population carries some H. pylori bacteria, but most will never have symptoms.

Symptoms of H. pylori infection include:

  • nausea
  • vomiting
  • burping
  • bloating
  • weight loss
  • an ache or pain in your abdomen

Complications can include ulcers, inflammation of your stomach lining and small intestine, and stomach cancer.

Learn more: Chronic gastritis »

Treatment for H. pylori infection includes antibiotics and acid suppression drugs. Follow-up testing may be recommended to see if the treatment is working.

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